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ORAL-HIV TEST

Treatment of HIV

Symptoms of HIV

General Information

Testing with an OraSure® HIV-1 Oral Specimen Collection Device is a safe, easy, and reliable way to test for HIV-1 antibodies. Testing with the OraSure® HIV-1 Oral Specimen Collection Device requires no blood or needles and has been shown to be more than 99% accurate.
OraSure® HIV-1 uses a specially treated cotton fiber pad attached to a nylon stick which is placed between the lower cheek and gum and left for 2-5 minutes. The OraSure® HIV-1 collection pad draws IgG antibodies out of the tissues of the cheek and gum. This sample, called oral mucosal transudate, contains far fewer contaminants than typically found in saliva. If present, antibodies to the HIV-1 virus will be collected in this sample.
The pad is then placed in the OraSure® HIV-1 transport vial. This vial contains preservative which will keep the sample stable for up to 21 days at 39° F to 98° F. The sample is then sent off to a qualified OraSure® HIV-1 testing laboratory for analysis using the OraSure® HIV-1 testing algorithm .
The tests performed at the laboratory test for antibodies to the HIV-1 virus, not the virus itself. This is why OraSure® HIV-1 can test for HIV-1, but the virus is not known to be transmittable through oral fluids.

Oral Fluid Specimen
Collection

Subject swabs once around other gums

Insert device into
vial

	Start timer
	Read at 20 min (not later than 60 min)

Non-reactive result

	Only control area show line
	No line in test area

Reactive result

	Control and test lines present
	may not be of similar intensities

Invalid result

No Control

The special pad is placed between the lower gum and inner cheek and left there for two minutes.

The OraSure system draws HIV antibodies out of the tissues of the cheek and gum. The virus itself is rarely ever found in oral fluid.

This sample, called mucosal ransudate,contains far fewer contaminants than typically found in saliva.

What is the difference between saliva
and mucosal transudate?

Oral mucosal transudate has high oncentrations of IgG; saliva has practically none. Oral mucosal transudate comes from the tissues of the cheek and gum; saliva comes from the salivary glands.